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Melatonin activates the Nrf2-ARE pathway when it protects against early brain injury in a subarachnoid hemorrhage model

✍ Scribed by Zhong Wang; Chao Ma; Cheng-Jie Meng; Guo-Qing Zhu; Xue-Bo Sun; Lei Huo; Jian Zhang; Hui-Xiang Liu; Wei-Chun He; Xu-Ming Shen; Zhang Shu; Gang Chen

Book ID: 111264950
Publisher: John Wiley and Sons
Year: 2012
Tongue: English
Weight: 430 KB
Volume: 53
Category: Article
ISSN: 0742-3098
DOI: 10.1111/j.1600-079x.2012.00978.x

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## Abstract The nuclear factor erythroid 2‐related factor 2 and antioxidant‐response element (Nrf2‐ARE) pathway is a key regulator for modulating inflammation and oxidative damage, which are involved in the pathogenesis of early brain injury (EBI) after subarachnoid hemorrhage (SAH). Previous studi