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Melanoma-specific tumor-infiltrating lymphocytes but not circulating melanoma-specific T cells may predict survival in resected advanced-stage melanoma patients

โœ Scribed by J. B. A. G. Haanen; A. Baars; R. Gomez; P. Weder; M. Smits; T. D. de Gruijl; B. M. E. von Blomberg; E. Bloemena; R. J. Scheper; S. M. van Ham; H. M. Pinedo; A. J. M. van den Eertwegh


Publisher
Springer-Verlag
Year
2005
Tongue
English
Weight
234 KB
Volume
55
Category
Article
ISSN
0340-7004

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Human autologous tumor-specific T-helper 2 (Th2) cells were investigated in melanoma tumor-infiltrating lymphocytes FILS). Both a CD4+ T-cell line and its 5 potential T-cell clones established from TlLs of a patient with metastatic melanoma produced significant levels of IL-4, IL-6, IL-10 and granul