Melanoma-specific expression in first-generation adenoviral vectors in vitro and in vivo — use of the human tyrosinase promoter with human enhancers

The invasive potential of human melanoma

The invasive potential of human melanoma cell lines correlates with their ability to alter fibroblast gene expression in vitro and the stromal microenvironment in vivo

✍ Ling Li; Bojan Dragulev; Paola Zigrino; Cornelia Mauch; Jay W. Fox 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 385 KB 👁 1 views

## Abstract The tumor microenvironment is thought to play an important role in invasion and metastasis. Previously, we have shown that signaling from melanoma cells can alter the gene expression profiles of fibroblasts __in vitro__ and __in vivo__. To investigate whether the capacity to signal fibr