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Melanoma risk associated with MC1R gene variants in Latvia and the functional analysis of rare variants

✍ Scribed by Ozola, Aija; Azarjana, Kristīne; Doniņa, Simona; Proboka, Guna; Mandrika, Ilona; Petrovska, Ramona; Čēma, Ingrīda; Heisele, Olita; Eņģele, Ludmila; Štreinerte, Baiba; Pjanova, Dace

Book ID
121466285
Publisher
Elsevier
Year
2013
Tongue
English
Weight
744 KB
Volume
206
Category
Article
ISSN
2210-7762

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## Abstract We sought to examine the association between MC1R variants and the risk of melanoma and breast cancer in Polish population. We also determined the prevalence of compound heterozygous carriers of MC1R and CDKN2A (A148T) variants. We examined 500 unselected melanoma cases, 511 consecutive