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Melanoma genetics: An update with focus on the CDKN2A(p16)/ARF tumor suppressors

✍ Scribed by Michael Piepkorn


Book ID
117844486
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
260 KB
Volume
42
Category
Article
ISSN
1097-6787

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The tumor suppressor gene CDKN2A (MTS1/p16), located on chromosome 9p21, is inactivated in a variety of tumors including melanomas and tumors of the biliary tract, pancreas, and stomach. The aim of the present study was to determine whether this gene is inactivated in hepatocellular carcinoma (HCC).