𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Melanocyte-specific, cytotoxic T cell responses in vitiligo: the effective variant of melanoma immunity?

✍ Scribed by Garbelli, Silvia ;Mantovani, Stefania ;Palermo, Belinda ;Giachino, Claudia


Book ID
111259932
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
89 KB
Volume
18
Category
Article
ISSN
0893-5785

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Qualitative difference between the cytot
✍ Belinda Palermo; Silvia Garbelli; Stefania Mantovani; Elisabetta Scoccia; Gian A πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 253 KB πŸ‘ 2 views

Vitiligo is a skin disorder characterized by depigmented macules secondary to melanocyte loss. An unusual facet is its relation to melanoma: Cytotoxic T lymphocytes directed to melanocyte antigens are found in both conditions and imply a breakdown of tolerance, yet the resulting immune reaction is t

Inverse relationship of melanocyte diffe
✍ Elke JΓ€ger; Mark Ringhoffer; Julia Karbach; Michael Arand; Franz Oesch; Alexande πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 French βš– 822 KB

Antigenic peptides derived from differentiation antigens of the melanocyte lineage were recently identified in human melanomas as targets for MHC-restricted cytotoxic T lymphocytes (CTL). CTL directed against peptides derived from the Melan A/MART-I, tyrosinase and gp100/Pme117 antigens can be detec

Human melanoma therapy in the SCID mouse
✍ BjΓΆrn Cochlovius; Astrid Perschl; Gosse J. Adema; Margot ZΓΆller πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 French βš– 102 KB πŸ‘ 2 views

The adoptive transfer of tumor-specific cytotoxic T cells (CTL) offers a promising perspective in cancer immunotherapy. However, the ex vivo-generated T lymphocytes are mostly IL-2-dependent. Here we explored the possibility of circumventing the requirement for IL-2, known for severe side effects in