Melanocortin receptors and antagonists r
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SiobhΓ‘n Jordan; Ian J. Jackson
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Article
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1998
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John Wiley and Sons
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English
β 52 KB
The action of two genetic loci-agouti and the melanocortin receptor-1 (Mc1r)have opposing effects in the control of mammalian pigmentation and ultimately determine the color of the pigment produced. In a recent paper, Ollmann et al. confirmed that the agouti protein acts via the Mc1r. They show that