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Melanocortin mediated inhibition of feeding behavior in rats

✍ Scribed by B Murphy; C.N Nunes; J.J Ronan; C.M Harper; M.J Beall; M Hanaway; A.M Fairhurst; L.H.T Van der Ploeg; D.E Maclntyre; T.N Mellin


Book ID
114118413
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
790 KB
Volume
32
Category
Article
ISSN
0143-4179

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THIP inhibits feeding behavior in fasted
✍ Nadine Blavet; Francis V. Feudis; FranΓ§ois Clostre πŸ“‚ Article πŸ“… 1982 πŸ› Springer 🌐 English βš– 467 KB

The effects of 4,5,6,7-tetrahydroisoxazolo-[5,4-c]pyridin-3-ol (THIP) were compared with those of d-amphetamine and GABA in fasted rats. Intravenously-. administered THIP produced a dose-dependent decrease in food consumption (EDso ~-1.5 mg/kg) by an action that was not reversed by prior subcutaneou