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Melanocortin-4 receptor-mediated inhibition of apoptosis in immortalized hypothalamic neurons via mitogen-activated protein kinase

✍ Scribed by Biaoxin Chai; Ji-Yao Li; Weizhen Zhang; Erika Newman; John Ammori; Michael W. Mulholland

Book ID: 116831165
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 921 KB
Volume: 27
Category: Article
ISSN: 0196-9781
DOI: 10.1016/j.peptides.2006.05.005

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## Abstract Peroxisome proliferator‐activated receptor gamma coactivator 1α (PGC‐1α) coactivates a number of transcription factors critical for mitochondrial biogenesis. Previously, we found that the expression of PGC‐1α is governed by neuronal activity, but the signaling mechanism is poorly unders