Melan-A/Mart-1 expression in various melanocytic lesions and in non-melanocytic soft tissue tumours
β Scribed by Z Orosz
- Book ID
- 108778785
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 401 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0309-0167
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From the peripheral blood lymphocytes (PBLs) of melanoma patient SK29(AV) we have previously isolated 2 independent cytolytic T lymphocyte (CTL) clones (CTL7/147 and CTL13/211), which lysed autologous tumor cells in association with HLA-B45.1. As demonstrated here, both CTL clones were directed agai
## Abstract Previous studies indicate that the nonclassical class I HLAβG antigen, whose physiologic expression is mainly restricted to placenta, is upregulated in melanoma, renal carcinoma, lung carcinoma, glioblastoma and ovarian carcinoma, where its inhibitory effect on cytotoxic effector cells