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MEK1 activation by PAK: A novel mechanism

✍ Scribed by Electa R. Park; Scott T. Eblen; Andrew D. Catling

Book ID
113528063
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
661 KB
Volume
19
Category
Article
ISSN
0898-6568

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## Abstract As activation of the Ras/Raf/MEK/ERK pathway is a critical component of M‐CSF‐promoted osteoclast survival, determining specific mechanism by which M‐CSF activates this signal transduction pathway is paramount towards advancing treatment of pathological conditions resulting in increased