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Meiotic consequences of pericentric inversions of chromosome 13

✍ Scribed by Wenger, S. L. ;Steele, M. W. ;Opitz, John M.

Book ID
101440312
Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
443 KB
Volume
9
Category
Article
ISSN
0148-7299

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Two cases of pericentric inversion of chromosome 12 are presented, one 46,XX,inv(12)(p13;q11) and the other was also a heterozygotic carrier of the inversion. These inversions were detected among 4035 cytogenetic analyses carried out in patients with psychosomatic retardation and/or malformations (3

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We investigated 33 individuals (21 carriers) from one family with a pericentric inversion involving a large part of chromosome 1 (1p36.1----1q32). In addition, we investigated 15 individuals (10 carriers) from another family with a paracentric inversion of a small part of chromosome 1 (1p32----1p36.