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Megakaryoblastic leukemia in an infant: Establishment of a megakaryocytic tumor cell line in athymic nude mice

✍ Scribed by David P. Witte; Richard E. Harris; Laura J. Jenski; Beatrice C. Lampkin

Publisher: John Wiley and Sons
Year: 1986
Tongue: English
Weight: 936 KB
Volume: 58
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(19860715)58:2<238::aid-cncr2820580207>3.0.co;2-#

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## Abstract The loss of the Y chromosome is a frequent numerical chromosomal abnormality observed in human prostate cancer. In cancer, loss of specific genetic material frequently accompanies simultaneous inactivation of tumor suppressor genes. It is not known whether the Y chromosome harbors such