Medulloblastoma in association with the Coffin-Siris syndrome

✍ Scribed by Lynn Rogers; Jogi Pattisapu; Robert R. Smith; Paul Parker

• Book ID: 104697465
• Publisher: Springer
• Year: 1988
• Tongue: English
• Weight: 706 KB
• Volume: 4
• Category: Article
• ISSN: 0256-7040
• DOI: 10.1007/bf00274083

✦ Synopsis

An 8-year old patient with Coffin-Siris syndrome is presented, who was found to have a medulloblastoma during the evaluation of apnea and ventilator dependency. Although several cases of Dandy Walker cysts and one case of brain-stem heterotopia have been described in this rare syndrome, this is the first report of medulloblastoma in a patient with Coffin-Siris syndrome. Possible pathogenetic mechanisms are briefly discussed.