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Medullary thyroid cancer: RET testing of an archival material

✍ Scribed by Christian Godballe; Gita Jørgensen; Anne-Marie Gerdes; Annelise S. Krogdahl; Anne Tybjærg-Hansen; Finn C. Nielsen

Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
131 KB
Volume
267
Category
Article
ISSN
0302-9530

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✍ Marios Kambouris; Charles E. Jackson; Gerald L. Feldman 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 1006 KB

Communicated by B w e A.J. Pondei Multiple endocrine neoplasia type 2 [MEN 21 is an autosomal dominant cancer syndrome with two subtypes, 2A and 2B. MEN 2A and medullary thyroid cancer [MTC] are caused by >25 different point mutations in exons 10, 11, and 13 of the RET proto-oncogene, whereas MEN 2B