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Mediators of PGE2 synthesis and signalling downstream of COX-2 represent potential targets for the prevention/treatment of colorectal cancer

✍ Scribed by Simon Chell; Abderrahmane Kadi; Ann Caroline Williams; Christos Paraskeva


Book ID
113486630
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
589 KB
Volume
1766
Category
Article
ISSN
0304-419X

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Cyclooxygenase-2: A novel molecular targ
✍ Derrick T. Lin; Kotha Subbaramaiah; Jatin P. Shah; Andrew J. Dannenberg; Jay O. πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 117 KB πŸ‘ 1 views

## Abstract Cyclooxygenase‐2 (COX‐2), an enzyme that catalyzes the synthesis of prostaglandins, is overexpressed in a variety of premalignant and malignant conditions, including oral leukoplakia and squamous cell carcinoma of the head and neck. Increased levels of COX‐2 may contribute to carcinogen