Mediators of inflammation

✍ Scribed by Rosalba Sacca; Carolyn A Cuff; Nancy H Ruddle

• Book ID: 104358802
• Publisher: Elsevier Science
• Year: 1997
• Tongue: English
• Weight: 785 KB
• Volume: 9
• Category: Article
• ISSN: 0952-7915
• DOI: 10.1016/s0952-7915(97)80189-6

✦ Synopsis

Therapeutic studies and genetically engineered animals have elucidated the inflammatory roles of cytokines and chemokines in autoimmune disease. Most unexpected has been a continuum of recent evidence demonstrating that inflammatory mediators are crucial in lymphoid organ development, thus suggesting that these hitherto unrelated processes have common elements with implications for determinant spreading.