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Mediation of pepsinogen secretion from guinea pig chief cells by Ca2+/calmodulin-dependent protein kinase II and its autophosphorylation

โœ Scribed by T. Joh; N. Okayama; M. Itoh; T. Miyamoto; T. Takeuchi; T. Suzuki; T. Kato


Book ID
118880481
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
169 KB
Volume
108
Category
Article
ISSN
0016-5085

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In gastric chief cells, agents that activate protein kinase C (PKC) stimulate pepsinogen secretion and phosphorylation of an acidic 72-kDa protein. The isoelectric point and molecular mass of this protein are similar to those for a common PKC substrate; the MARCKS (for Myristoylated Alanine-Rich C K