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Mediastinal germ cell tumor with secondary nongerm cell malignancy, and extensive hematopoietic activity: Pathology, DNA-ploidy, and karyotyping

✍ Scribed by J.Wolter Oosterhuis; Eva van den Berg; Bauke de Jong; Wim Timens; Sérgio M.M.J. Castedo; Rene H.U. Rammeloo; Dirk Th. Sleijfer

Book ID
119104987
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
882 KB
Volume
54
Category
Article
ISSN
0165-4608

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✍ K. C. Lee; Attilio Orazi; Richard S. Neiman; Thomas M. Ulbright; Craig R. Nichol 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 229 KB 👁 2 views

Orazi et al.' reported data on six patients with secondary leukemia who were seen initially with mediastinal germ cell tumor. They hypothesized that the leukemias are derived from pluripotent stem cells found in the yolk sac tumor component. Given the discovery of a marrow stem cell that can give ri