Mediastinal germ cell tumor in a child with precocious puberty and Klinefelter syndrome
β Scribed by Gregory G Bebb; Frederic W Grannis Jr; Isaac B Paz; Marilyn L Slovak; Robert Chilcote
- Book ID
- 117039094
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 219 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0003-4975
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π SIMILAR VOLUMES
W e describe a boy who developed precocious puberty resulting from chorionic gonadotropin produced by a mediastinal germ cell tumor. Following tumor removal he began spontaneous precocious sexual development which was treated and then arrested spontaneously. Investigation of this arrested puberty es
Klinefelter's syndrome is a genetic disorder of male sexual differentiation characterized by an XXY karyotype. Although considered a benign condition, it is associated with several types of malignancies, including mediastinal germ-cell neoplasm. In addition, Klinefelter's syndrome has been rarely as