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Median raphe, but not dorsal raphe, application of the 5-HT1A agonist 8-OH-DPAT stimulates rat motor activity

โœ Scribed by Viveka Hillegaart; Stephan Hjorth

Book ID
115882534
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
328 KB
Volume
160
Category
Article
ISSN
0014-2999

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Chronic administration of the 5-HT1A receptor agonist 8-OH-DPAT differentially desensitizes 5-HT1A autoreceptors of the dorsal and median raphe nuclei
โœ Deborah S. Kreiss; Irwin Lucki ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 192 KB ๐Ÿ‘ 1 views

The present study investigated alterations of the regulation of serotonin (5-hydroxytryptamine; 5-HT) release by 5-HT 1A autoreceptors following single and repeated treatment with the 5-HT 1A receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). Rats were pretreated with 8-OH-DPAT (1.