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MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

✍ Scribed by Chahrour, M.; Jung, S. Y.; Shaw, C.; Zhou, X.; Wong, S. T. C.; Qin, J.; Zoghbi, H. Y.


Book ID
118209154
Publisher
American Association for the Advancement of Science
Year
2008
Tongue
English
Weight
216 KB
Volume
320
Category
Article
ISSN
0036-8075

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## Abstract ## Objective Both genetic and epigenetic factors play an important role in the pathogenesis of lupus. The aim of this study was to examine methyl‐CpG–binding protein 2 gene (__MECP2__) polymorphisms in a large cohort of patients with lupus and control subjects, and to determine the fun