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Mechanistic Studies on the Repair of a Novel DNA Photolesion: The Spore Photoproduct

✍ Scribed by Mehl, Ryan A.; Begley, Tadhg P.

Book ID
126018318
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
36 KB
Volume
1
Category
Article
ISSN
1523-7060

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## Abstract UV light is one of the major causes of DNA damage. In spore DNA, due to an unusual packing of the genetic material, a special spore photoproduct lesion (SP lesion) is formed, which is repaired by the enzyme spore photoproduct lyase (Spl), a radical __S__‐adenosylmethionine (SAM) enzyme.