Mechanistic Studies on the Reaction between Cob(II)alamin and Peroxynitrite: Evidence for a Dual Role for Cob(II)alamin as a Scavenger of Peroxynitrous Acid and Nitrogen Dioxide

Kinetic Studies on the Reaction between

Kinetic Studies on the Reaction between Cob(I)alamin and Peroxynitrite: Rapid Oxidation of Cob(I)alamin to Cob(II)alamin by Peroxynitrous Acid

✍ Dr. Riya Mukherjee; Dr. Nicola E. Brasch 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 260 KB 👁 1 views

There is currently much interest in the biochemical reactivity of peroxynitrite/peroxynitrous acid (ONOO À / ONOOH; pK a(ONOOH) = 6.8), [1] a strong oxidizing, hydroxylating and/or nitrating agent formed by the diffusion controlled reaction of nitric oxide with superoxide. [1] Elevated peroxynitrite