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Mechanistic studies of the ring opening reactions of [1,2,3]triazolo[1,5-a]pyridines

✍ Scribed by Belén Abarca; Rafael Ballesteros; Gemma Rodrigo; Gurnos Jones; Jaume Veciana; José Vidal-Gancedo

Book ID
108379044
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
310 KB
Volume
54
Category
Article
ISSN
0040-4020

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✍ Belen Abarca; Fatemeh Mojarred; Gurnos Jones; Caroline Phillips; Nadine Ng; Jona 📂 Article 📅 1988 🏛 Elsevier Science 🌐 French ⚖ 721 KB

Nucleophilic substitution of 5-bromotriazoloisoquinoline (3) and of 7-bromo-3-methyltriazolopyridine (6) proceeds readily to give a range of 5-substituted triazoloisoquinolines (4a)-(4e), and of 7-substituted triazolopyridines (7a)-(7h) respectively. Triazoloisoquinolines have been converted into 1,