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Mechanistic studies of the reduction of daunomycin with sodium borohydride. Formation and reaction of borate esters

โœ Scribed by Schweitzer, Barbara Ann; Egholm, Michael; Koch, Tad H.


Book ID
126003774
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
906 KB
Volume
114
Category
Article
ISSN
0002-7863

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The reduction of N-alkyl pyridinium salts with sodium borohydride is a well-known reaction, yielding in most cases the corresponding 1, 2, 3, C-tetrahydropyridine derivatives. 1 The mechanistic aspects of this reaction have been studied and a mechanism proposed. 2 We wish to report our studies on t