As part of a long-term effort to understand the structure/function relationship between chemical permeation enhancers and skin permeation enhancement, the present study examined the influence of hydrocarbon chain branching on the effectiveness of skin permeation enhancers of the type that possesses
Mechanistic studies of the 1-alkyl-2-pyrrolidones as skin permeation enhancers
โ Scribed by Kunio Yoneto; Abdel-Halim Ghanem; William I. Higuchi; Kendall D. Peck; S. Kevin Li
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 713 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
In previous studies (Yoneto et al., 1995. J Pharm Sci 84:312-317; Kim et al., 1992. Int J Pharm 80:17-31; and Warner et al., 2001. J Pharm Sci 90:1143-53), the transport enhancing effects of four homologous series of enhancers-the n-alkanols, 1-alkyl-2-pyrrolidones, 1,2-alkanediols, and N,N-dimethyl
Previous investigations in our laboratory demonstrated how the polar head group and alkyl chain of amphiphilic chemical skin permeation enhancers contribute to enhancer potency. In those studies enhancers with n-alkyl chain lengths of eight or less were investigated. In order to investigate enhancer
## Abstract The interaction of 2,2โฒโbipyridine with dichloroโ[1โalkylโ2โ(ฮฑโnaphthylazo) imidazole]palladium(II) [Pd(ฮฑโNaiRโฒ)Cl~2~, **1**] and dichloroโ[1โalkylโ2โ(ฮฒโnaphthylazo) imidazole] palladium(II) [Pd(ฮฒโNaiRโฒ)Cl~2~, **2**] complexes {where alkyl Rโฒ = Me (**a**), Et (**b**) or Bz (**c**)} in a