Synthesis of Chiral 1,3-Diamines Derived
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Dr. Koichi Kodama; Kazuyuki Sugawara; Prof. Takuji Hirose
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Article
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2011
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John Wiley and Sons
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English
⚖ 438 KB
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## Abstract In this study, 13 different chiral 1,3‐diamines were synthesized from (−)‐__cis__‐2‐benzamidocyclohexanecarboxylic acid. They were successfully applied as ligands in the Cu‐catalyzed asymmetric Henry reaction between benzaldehyde and nitromethane. It was confirmed that the enantioselect