The mechanism of action of quinocarmycin
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Ryunosuke Kanamaru; Yukari Konishi; Chikashi Ishioka; Hideki Kakuta; Toshiaki Sa
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Article
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1988
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Springer
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English
β 368 KB
The effects of the antitumor antibiotic, quinocarmycin citrate (KW 2152), on L1210 cells were studied in vitro. The cellular growth was completely inhibited at 10(-6) M KW 2152, and after 2 days no viable cell was seen. The incorporation of 3H-thymidine, 3H-uridine, or 3H-leucine into the acid-insol