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Mechanistic aspects of the biogenesis of rose oxide in Pelargonium graveolens L'Héritier

✍ Scribed by Matthias Wüst; Annette Rexroth; Thomas Beck; Armin Mosandl


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
184 KB
Volume
10
Category
Article
ISSN
0899-0042

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✦ Synopsis


Mechanistic aspects of the biogenesis of the chiral monoterpenoid rose oxide in Pelargonium graveolens L'He ´ritier are investigated using deuterium-labelled precursors. After administration of the precursors using the cut-stem method, the dynamic headspace extracts of the plants are analysed using multidimensional gas chromatography-mass spectrometry (enantio-MDGC-MS). It is unequivocally shown that this plant is able to convert citronellol and menthocitronellol into cis-/trans-rose oxide. Menthocitronellol is converted into rose oxide with a clearly detectable enantiodiscrimination. These facts may be explained with the presence of an oxidase, which is able to oxidize citronellol and menthocitronellol in allylic position. A photooxygenation mechanism including singlet oxygen as the oxidizing agent is rather unlikely.