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Mechanistic aspects of coenzyme B12-dependent rearrangements: organometallics as free radical precursors

✍ Scribed by Jack Halpern


Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
232 KB
Volume
79
Category
Article
ISSN
0020-1693

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Reactions related to coenzyme B12 depend
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Free radicals generated from the methylmalonylcoenzyme A mutase model substrates (3) and (4) by chromium(ll) reduction, or by pyrolysis of the analogous cobaloximes, underwent [1,2]-migration only in the acyl series (R = Ph, Me) and not the critical ester series (R = OEt, SBu). The mechanism of the