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Mechanisms Which Mediate the Antiapoptotic Effects of Angiopoietin-1 on Endothelial Cells

✍ Scribed by Rania Harfouche; Haroutioun M. Hasséssian; Yang Guo; Valérie Faivre; Coimbatore B. Srikant; George D. Yancopoulos; Sabah N.A. Hussain

Book ID
115641295
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
297 KB
Volume
64
Category
Article
ISSN
0026-2862

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## Abstract Angiopoietin‐1 (Ang1) and vascular endothelial growth factor (VEGF) cooperate in migration and survival of endothelial cells by activation of phosphatidylinositol‐3 (PI‐3) kinase and mitogen activating protein (MAP) kinase pathways. However, Ang1 opposes the effect of VEGF on vascular p