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Mechanisms underlying β2-adrenoceptor-mediated nitric oxide generation by human umbilical vein endothelial cells

✍ Scribed by Lindsay R. Queen; Yong Ji; Biao Xu; Lora Young; Kang Yao; Amanda W. Wyatt; David J. Rowlands; Richard C. M. Siow; Giovanni E. Mann; Albert Ferro

Book ID: 110115137
Publisher: Cambridge University Press
Year: 2006
Tongue: English
Weight: 300 KB
Volume: 576
Category: Article
ISSN: 0022-3751
DOI: 10.1113/jphysiol.2006.115998

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## Abstract Alterations of nitric oxide contribute to post‐flight orthostatic intolerance. The aim of this study was to investigate the changes of inducible nitric oxide synthase (iNOS) and the mechanisms underlying regulation of iNOS by simulated microgravity in human umbilical vein endothelial ce