MECHANISMS UNDERLYING UBIQUITINATION
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Pickart, Cecile M.
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Article
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2001
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Annual Reviews
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English
β 420 KB
βͺ Abstractβ The conjugation of ubiquitin to other cellular proteins regulates a broad range of eukaryotic cell functions. The high efficiency and exquisite selectivity of ubiquitination reactions reflect the properties of enzymes known as ubiquitin-protein ligases or E3s. An E3 recognizes its substr