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Mechanisms of p53-induced apoptosis: in search of genes which are regulated during p53-mediated cell death

✍ Scribed by Caroline Choisy-Rossi; Philippe Reisdorf; Elisheva Yonish-Rouach


Book ID
119539599
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
209 KB
Volume
102-103
Category
Article
ISSN
0378-4274

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## Abstract Diepoxybutane (DEB) is the most potent active metabolite of the environmental chemical 1,3‐butadiene (BD). BD is a known mutagen and human carcinogen and possesses multisystems organ toxicity. We previously reported the elevation of p53 in human TK6 lymphoblasts undergoing DEB‐induced a