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Mechanisms of oxidative damage by myeloperoxidase in atherosclerosis and other inflammatory disorders

โœ Scribed by Jay W Heinecke

Book ID
114054168
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
485 KB
Volume
133
Category
Article
ISSN
1532-6543

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Oxidation of low density lipoproteins (LDL) in the presence of myeloperoxidase and subsequent uptake of the oxidized LDL by specialized receptors on macrophages has been suggested as an initiating event of atherosclerosis. Oxidized fatty acid chains within the glycerophospholipids of LDL have been i