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Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs)

✍ Scribed by Duensing, Anette; Medeiros, Fabiola; McConarty, Bryna; Joseph, Nora E; Panigrahy, Dipak; Singer, Samuel; Fletcher, Christopher DM; Demetri, George D; Fletcher, Jonathan A


Book ID
110068601
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
247 KB
Volume
23
Category
Article
ISSN
0950-9232

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## Abstract ## Background and objective to analyze the frequency and spectrum of KIT and platelet‐derived growth factor receptor‐alpha (PDGFRA) gene in a large series of study and to explore the clinical implication of mutations in the gastrointestinal stromal tumors (GISTs) in China. ## Method