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Mechanisms of Na+/H+ Exchanger Isoform 3 Gene Proximal Promoter Modulation by Parathyroid Hormone

โœ Scribed by Bezerra, Camila N.A.; Neri, Elida A.; Queiroz-Leite, Gabriella D.; Reboucas, Nancy A.


Book ID
122055834
Publisher
Biophysical Society
Year
2013
Tongue
English
Weight
40 KB
Volume
104
Category
Article
ISSN
0006-3495

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## Abstract Incubation with serum modulates the transporters that regulate intracellular pH (pH~i~) in articular chondrocytes, upregulating acid extrusion by Na^+^โ€H^+^ exchange (NHE). There is stimulation of NHE1, together with induction of NHE3 activity. These isoforms exhibit differential respon