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Mechanisms of MAPK kinase-independent p38-MAPK activation

โœ Scribed by Rekha Bassi; Richard Heads; Michael Marber

Book ID
116985543
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
74 KB
Volume
44
Category
Article
ISSN
0022-2828

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## Abstract Activation of p38 MAPK is a critical requisite for the therapeutics activity of the antitumor agent cisplatin. In this sense, a growing body of evidences supports the role of cโ€Abl as a major determinant of p38 MAPK activation, especially in response to genotoxic stress when triggered b