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Mechanisms of ligand-mediated inhibition in Notch signaling activity in Drosophila

✍ Scribed by Ulla-Maj Fiuza; Thomas Klein; Alfonso Martinez Arias; Penelope Hayward

Book ID
118283278
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
635 KB
Volume
239
Category
Article
ISSN
1058-8388

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## Abstract Notch signaling plays an essential role in the processes of embryogenesis and cellular differentiation, and it is believed that the oncogenic effects of dysregulated Notch signaling are an anomalous reflection of the normal functions of this cascade. Nonetheless, the cellular events ass