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Mechanisms of Interferon-β-Induced Survival in Fetal and Neonatal Primary Astrocytes

✍ Scribed by Barca, Olga; Seoane, Marcos; Ferré, Susana; Prieto, Jose M.; Lema, Manuela; Señarís, Rosa; Arce, Víctor M.


Book ID
120405317
Publisher
S. Karger AG
Year
2007
Tongue
English
Weight
218 KB
Volume
14
Category
Article
ISSN
1021-7401

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## Abstract This study describes the involvement of the p38 mitogen‐activated protein kinase (MAPK) during interferon‐γ (IFN‐γ) signaling in fetal brain astrocytes. In some pathological conditions of brain, p38 MAPK transduces stress‐related signals, increases expression of proinflammatory cytokine