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Mechanisms of histamine-induced intracellular Ca2+ release and extracellular Ca2+ entry in MG63 human osteosarcoma cells

โœ Scribed by Kam Chung Lee; Li-Ling Tseng; Yu-Chih Chen; Jun-Wen Wang; Cheng-Hsien Lu; Jin-Shiung Cheng; Jue-Long Wang; Yuk-Keung Lo; Chung-Ren Jan

Book ID
113992658
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
235 KB
Volume
61
Category
Article
ISSN
0006-2952

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Phospholipase A2-independent Ca2+ entry
Phospholipase A2-independent Ca2+ entry and subsequent apoptosis induced by melittin in human MG63 osteosarcoma cells
โœ Sau-Tung Chu; He-Hsiung Cheng; Chun-Jen Huang; Hong-Chiang Chang; Chao-Chuan Chi ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 363 KB

Melittin, a peptide from bee venom, is thought to be a phospholipase A(2) activator and Ca(2+) influx inducer that can evoke cell death in different cell types. However, the effect of melittin on cytosolic free Ca(2+) concentration ([Ca(2+)](i)) and viability has not been explored in human osteoblas