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Mechanisms of effect of orotic acid on growth and development of young rats

✍ Scribed by T. A. Bal'magiya; G. A. Antonova; N. A. Khodorova

Publisher
Springer US
Year
1975
Tongue
English
Weight
280 KB
Volume
79
Category
Article
ISSN
0007-4888

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A marked tolerance to both analgesic and eataleptie effects of 20 mg/kg morphine hydroehloride was developed in rats during treatment with daily doses increasing from 20 to 120mg/kg s.c. within 11 days. Daily administration of 100 mg/kg sodium orotate i.p. 14 days before and during treatment with mo