✦ LIBER ✦

Mechanisms of DNA bending

✍ Scribed by L James Maher III

Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 920 KB
Volume: 2
Category: Article
ISSN: 1367-5931
DOI: 10.1016/s1367-5931(98)80104-x

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✦ Synopsis

Genome packaging and gene regulation require DNA bending. Recent developments in the elucidation of the mechanisms involved in DNA bending include new X-ray structures (most notably that of the mammalian nucleosome) wherein DNA is bent, controversy surrounding interpretation of DNA-bending experiments with basic-leucine zipper proteins, studies of electrostatic effects in DNA bending, and the design of artificial DNA-bending ligands.

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