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Mechanisms of Dendritic Cell Trafficking Across the Blood–brain Barrier

✍ Scribed by Sagar, Divya; Foss, Catherine; Baz, Rasha; Pomper, Martin G.; Khan, Zafar K.; Jain, Pooja

Book ID
107381792
Publisher
Springer US
Year
2011
Tongue
English
Weight
618 KB
Volume
7
Category
Article
ISSN
1557-1890

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✍ Michael Pollay 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 English ⚖ 476 KB

## Abstract In adult rats, using the single‐pass brain uptake technique with a tritiated water standard, L‐phenylalanine was shown to enter brain across the blood‐brain barrier (BBB) by both a saturable and diffusionary process. A kinetic analysis of the data revealed Michaelis constant (K~a~) of 0