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Mechanisms of decreased Vitamin D 1α-hydroxylase activity in prostate cancer cells

✍ Scribed by Jian Feng Ma; Larisa Nonn; Moray J Campbell; Martin Hewison; David Feldman; Donna M Peehl


Book ID
116733540
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
381 KB
Volume
221
Category
Article
ISSN
0303-7207

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Prostatic 25-hydroxyvitamin D-1α-hydroxy
✍ Tai C. Chen; Lilin Wang; Lyman W. Whitlatch; John N. Flanagan; Michael F. Holick 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 137 KB

## Abstract Evidence suggests that vitamin D may have a protective role for prostate cancer. 1α,25‐Dihydroxyvitamin D [1α,25(OH)~2~D] inhibits growth and induces differentiation of prostate cells. 25‐Hydroxyvitamin D‐1α‐hydroxylase [1α‐OHase], the enzyme that is responsible for the synthesis of 1α,