Mechanisms of cycloheximide-induced apoptosis in liver cells
โ Scribed by Alice V Alessenko; Peter Ya Boikov; Galina N Filippova; Alexey V Khrenov; Anatoliy S Loginov; Elena D Makarieva
- Book ID
- 117108251
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 575 KB
- Volume
- 416
- Category
- Article
- ISSN
- 0014-5793
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Magnolol has been reported to have anticancer activity. In this study we found that treatment with 100 ฮผm magnolol induced apoptosis in cultured human hepatoma (Hep G2) and colon cancer (COLO 205) cell lines but not in human untransformed gingival fibroblasts and human umbilical vein en
Cells of the human promyelocytic HL-60 line, when treated with a variety of antitumor agents in the presence of the protein synthesis inhibitor cycloheximide (CHX), or with CHX alone, rapidly undergo apoptosis ("active cell death"). It is presumed, therefore, that such cells are "primed" to apoptosi