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Mechanisms of cellular cytotoxicity mediated by a recombinant antibody-IL2 fusion protein against human melanoma cells

✍ Scribed by Mayumi Naramura; Stephen D. Gillies; John Mendelsohn; Ralph A. Reisfeld; Barbara M. Mueller

Publisher: Elsevier Science
Year: 1993
Tongue: English
Weight: 624 KB
Volume: 39
Category: Article
ISSN: 0165-2478
DOI: 10.1016/0165-2478(93)90169-3

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## Abstract The specificity of cell‐mediated cytotoxicity against melanoma cells in vitro has been analyzed in a large number of studies with cells both from normal and melanoma subjects. As in a number of other, recent, similar human studies, no evidence for tumour specificity was found. Effector