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Mechanisms of cardioprotective effect of estradiol

✍ Scribed by A. Zh. Mambetova; A. I. Matyushin

Book ID
105573346
Publisher
Springer US
Year
2000
Tongue
English
Weight
265 KB
Volume
129
Category
Article
ISSN
0007-4888

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## Abstract The lysophospholipids sphingosine 1‐phosphate (S1P) and lysophosphosphatidic acid (LPA) reduce mortality in hypoxic cardiac myocytes. S1P is also cardioprotective in both mouse and rat models of cardiac ischemia/reperfusion (I/R) injury. Although these results are consistent with prior