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Mechanisms of bone loss and mode of action of antiresorptive therapies

โœ Scribed by H. Fleisch


Publisher
Springer-Verlag
Year
1996
Tongue
English
Weight
144 KB
Volume
6
Category
Article
ISSN
0937-941X

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Mechanisms of glucocorticoid action in b
โœ Dr. Anne M. Delany; Yu Dong; Ernesto Canalis ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 860 KB

Glucocorticoids play an important role in the normal regulation of bone remodeling; however continued exposure of bone to glucocorticoid excess results in osteoporosis. In vivo, glucocorticoids stimulate bone resorption and decrease bone formation, and in vitro studies have shown that while glucocor